In this lesson, we learn how to factor the difference of squares using the pattern a² - b² = (a - b)(a + b). We walk through three examples — starting with basic expressions like x² - 49, then moving on to cases that involve coefficients and higher powers, like 4x² - 25 and 72 - 2y⁴. You'll see how to first factor out the greatest common factor (GCF) and then apply the difference of squares pattern when possible.